mucholderthen:

SCIENTIFIC ILLUSTRATION:  Nucleosome
The Mediterranean Institute for Life Sciences
Split, Croatia

High resolution ray-traced model of a nucleosome, isolated on black.

A nucleosome is the basic unit of DNA packaging in eukaryotes, consisting of a segment of DNA wound in sequence around four histone protein cores.  This structure is often compared to thread wrapped around a spool.

Nucleosomes form the fundamental repeating units of eukaryotic chromatin, which is used to pack the large eukaryotic genomes into the nucleus while still ensuring appropriate access to it.  In mammalian cells approximately 2 m of linear DNA have to be packed into a nucleus of roughly 10 µm diameter.  

Nucleosomes are folded through a series of successively higher order structures to eventually form a chromosome; this both compacts DNA and creates an added layer of regulatory control, which ensures correct gene expression.

(Nucleosome - Wikipedia)

ladyxgaga:

Gaga spotted in New York City today

ladyxgaga:

Here’s a short video of Gaga’s father talking about ARTPOP at the Born Brave Bus in New York City.

Joe states that he thinks “Burqa” is the best song and that he believes the lead single will be released in August or September, though this is not confirmed.

ETA: Gaga’s father does not work with or for Gaga and/or her label and therefore does not know when ARTPOP or its singles will be released.

ladyxgaga:

Unretouched photo of Gaga by Mario Testino for Vogue US in 2011.

ladyxgaga:

A video of Gaga and Taylor Kinney attending a private screening of The Great Gatsby in New York City last night. 

HOLY FUCK!!!

this is how flyleaf should sound. i wont n will not get used to the new girl :/ sorry its just me.

AH MAH GAAD CYUUUUTE BUNNEH 

dvdp:

120515

ericjaxx:

laughingstation:

meeshmatched:

bahaha the black pug that comes out from the bottom left corner kills me with his excitement!

LOL!!